We investigated 20 adult patients with ADHD and 20 age-matched healthy controls. We found significantly smaller GMV in the right and left anterior cingulate cortex (ACC) but no GMV/WMV difference in the PFC, hippocampus and amygdala. No correlation was found between ADHD behavioral measures and MRI data. Our results might suggest that adults with ADHD exhibit smaller GMV in the ACC, as measured by VBM. Volumetric abnormalities in the brain of adult ADHD patients might be less pronounced than those found in SNS-032 children and adolescents, although the role played by chronic stimulant treatment
needs further investigation. (C) 2010 Elsevier Ireland Ltd. All rights reserved.”
“We report here the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, egret/China/Guangxi/2011, isolated from an egret in Guangxi Province, southern China. A phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that egret/China/Guangxi/2011 was phylogenetically close to genotype VIIa NDV, and the deduced amino acid sequence was R-112-R-R-K-R-F-117 at the fusion protein cleavage site. The whole nucleotide sequence had the highest homology (93.3%)
with the sequence of strain chicken/Sukorejo/019/10 (GenBank accession number HQ697255). This study will help us to understand the epidemiology and molecular characteristics of Newcastle disease virus in a migratory egret.”
“Therapeutic interventions that incorporate training in mindfulness meditation have become increasingly selleck chemical Endodeoxyribonuclease popular, but to date little is known about neural
mechanisms associated with these interventions. Mindfulness-Based Stress Reduction (MBSR), one of the most widely used mindfulness training programs, has been reported to produce positive effects on psychological well-being and to ameliorate symptoms of a number of disorders. Here, we report a controlled longitudinal study to investigate pre-post changes in brain gray matter concentration attributable to participation in an MBSR program. Anatomical magnetic resonance (MR) images from 16 healthy, meditation-naive participants were obtained before and after they underwent the 8-week program. Changes in gray matter concentration were investigated using voxel-based morphometry, and compared with a waiting list control group of 17 individuals. Analyses in a priori regions of interest confirmed increases in gray matter concentration within the left hippocampus. Whole brain analyses identified increases in the posterior cingulate cortex, the temporo-parietal junction, and the cerebellum in the MBSR group compared with the controls. The results suggest that participation in MBSR is associated with changes in gray matter concentration in brain regions involved in learning and memory processes, emotion regulation, self-referential processing, and perspective taking. (C) 2010 Elsevier Ireland Ltd. All rights reserved.