Values are reported as mean +/- 95% confidence interval.
Conclusion: This detailed assessment of collagen architecture could benefit the development of cartilage repair strategies intended to recreate functional collagen architecture. (C) 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.”
“Background: The aim of this population-based study was to determine the short-term prognosis of patients treated conservatively for spontaneous
intracerebral hemorrhage (ICH), a disease with a high rate of mortality. Methods: During a 39-month period beginning in October 2007, 594 patients (mean age 72 6 12 years; 52% female; median National Institutes of Health Stroke Scale [NIHSS] score 9) with spontaneous ICH were enrolled in this prospective, Ulixertinib clinical trial population-based study. Results: Of 594 patients, 74 (12%) died during hospitalization (10.3 +/- 7 days). Adjusted logistic regression analyses OICR-9429 research buy revealed that the in-hospital mortality rate was significantly associated with age >80 years (odds ratio [OR] 3.1; 95% confidence interval [CI] 1.3-7.5; P = .01), NIHSS score. 15 (OR 3.3; 95% CI 1.4-9.7; P = .007), unconsciousness at admission (OR 5.3; 95% CI 2.0-13.6;
P = .001), and cerebral edema detected by cranial computed tomography at admission (OR 14.7; 95% CI 6.2-34.6; P > .001). At hospital discharge, 329 patients (63%) agreed to participate in the inquiry. At 3 months of follow-up, 55 (18%) of 309 patients died. The 3-month mortality
rate correlated significantly with age >80 years (OR 3.5; 95% CI 1.4-8.7; P = .008), previous stroke (OR 4.1; 95% CI 1.6-10.3; P = .002), unconsciousness at admission (OR 5.7; 95% CI 2.4-13.9; P = .001), pneumonia suffered during hospitalization (OR 3.3; 95% CI 1.2-9.6; P = .02), and cerebral edema (OR 5.7; 95% CI 2.3-13.8; P > .001). Conclusions: Our study may help clinicians estimate the short-term prognosis of patients treated conservatively for ICH.”
“Background: Three-quarters of rehospitalizations ($44 billion DZNeP yearly estimated cost) may be avoidable. A screening tool for the detection of potential readmission may facilitate more efficient case management.
Hypothesis: An elevated red blood cell distribution width (RDW) is an independent predictor of hospital readmission in patients with unstable angina (UA) or non-ST-elevation myocardial infarction (NSTEMI).
Methods: The study is a retrospective observational cohort analysis of adults admitted in 2007 with UA or NSTEMI. Data were gathered by review of inpatient medical records. The rate of 30-day nonelective readmission and time to nonelective readmission were recorded until November 1, 2011, and compared by RDW group using the 95th percentile (16.3%) as a cutoff.
Results: The median follow-up time of the 503 subjects (average age, 65 +/- 13 years; 56% male) was 3.8 years (interquartile range: 0.3-4.3 years).