On the other hand, ZnO nanoparticles with a wide energy bandgap are an excellent, well-studied semiconductor, accompanied by shifting of the intrinsic band due to quantum confinement [3, 9–11]. Strong, tunable absorption and emission bands revealed in ZnO nanostructure, characterized by the particle size and the surrounding medium, have found uses in biosensing technology, electronics, photoelectronics, catalysis, and chemical FRAX597 concentration degradation. By nanoengineering these two materials into a single entity, the ensuing nanostructure would not only exercise the unique

properties of gold and the semiconductor, but also generate novel collective phenomena based on the interaction between Au and ZnO [12–15]. Such a structural nanoassembly can have the extra advantages of biocompatibility and low toxicity and afford an easy, effective contact between biological tissue and the nanoparticles, anticipated to be benign for biological JSH-23 detection, photocatalysis, and dye-sensitized solar

cells. Ranking in a variety of interesting structural forms, the synthesis of ZnO-Au nanoparticles has been performed for various purposes [16–21]. In addition, the natural coating of nanoparticle surfaces by an ultrathin film of biocompatible molecules is highly desirable for future biomedical applications, especially if done in situ during the synthesis process of the nanoparticles [3, 17]. We here report

the preparation of ZnO-Au hybrid nanoparticles by one-pot non-aqueous nanoemulsion with the triblock copolymer poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (PEO-PPO-PEO) as the surfactant. The copolymer has proved many distinctive merits, such as aqueous solubility, biocompatibility, non-charging, and non-toxicity, and is often used in a number of fields [22–26]. In nanoemulsion processes, the PEO-PPO-PEO molecules principally participate in the reactions as a surfactant, playing Ureohydrolase a role in stabilizing the nanoparticles formed and even acting as a reducing agent, as attested in our reports on long-term stable, highly crystalline, monosized Fe3O4/Ca3(PO4)2, Fe3O4/ZnO, Fe3O4/Au, and FeAu nanoparticles [3, 8, 27, 28]. In this work, the ZnO-Au nanoparticles prepared without a secondary surface modification were bi-phase dispersible. The characterization shows that such polymer-laced ZnO-Au nanoparticles are monosized and of high Selleck TSA HDAC crystallinity and possess excellent dispersibility and optical performance in both organic and aqueous medium.