5% ceiling effects. The scores for the individual COMI items correlated with their corresponding full-length reference questionnaire with varying strengths of correlation (0.33-0.84, P < 0.05). COMI whole scores showed a very good correlation with the “”multidimensional”" DPQ global score (Rho = 0.71). 55 patients (79%) returned a second questionnaire with no/minimal change in their back status. The reproducibility of individual COMI 5-point items was good, with
test-retest differences within one grade ranging from 89% for ‘social/work disability’ to 98% for ‘symptom-specific well-being’. The intraclass correlation Small molecule library supplier coefficient for the COMI whole score was 0.85 (95% CI 0.76-0.91).
In conclusion, the French version of this short, multidimensional questionnaire showed good psychometric properties, comparable to those reported for German Belnacasan and Spanish versions. The French COMI represents a valuable tool for future multicentre clinical studies and surgical registries (e.g. SSE Spine Tango) in French-speaking countries.”
“The key factors for the success of matrix solid-phase dispersion (MSPD) are its feasibility, flexibility, versatility, low costs and rapidity.
Furthermore, with MSPD, it is possible to perform, on a small sample aliquot, extraction and clean up in a single step. In recent years, the greatest innovation in the MSPD technique has been the employment of unusual supporting materials (i.e. highly selective molecularly-imprinted polymers and the less specific multi-walled carbon nanotubes), although traditional sorbent and supports are still widely employed. Another
novelty is the growing application of the multivariate statistical approach (experimental design) to optimize the click here extraction conditions.
The purpose of this review is to present a rapid overview of MSPD applied to specific matrices and an update on the latest trends and innovations in the field since 2009. We pay particular attention to unusual matrices, new rapid clean-up techniques, and comparison with other sample-preparation methods. (C) 2012 Elsevier Ltd. All rights reserved.”
“Background: Identification of the subset females with Turner syndrome who face especially high risk of aortic dissection is difficult, and more optimal risk assessment is pivotal in order to improve outcomes. This study aimed to provide comprehensive, dynamic mathematical models of aortic disease in Turner syndrome by use of cardiovascular magnetic resonance (CMR).
Methods: A prospective framework of long-term aortic follow-up was used, which comprised diameters of the thoracic aorta prospectively assessed at nine positions by CMR at the three points in time (baseline [n = 102, age 38 +/- 11 years], follow-up [after 2.4 +/- 0.4 years, n = 80] and end-of-study [after 4.8 +/- 0.5 years, n = 78]).